연구업적
Hong E-H, Kim J, Kim J-H, Lim D-S, Kim M, Kim J-Y. BIG2-ARF1-RhoA-mDia1 signaling regulates dendritic Golgi polarization in hippocampal neurons. Mol Neurobiol. (2018) Accepted.
Kang WK, Devare M, Kim J-Y. HST1 increases replicative lifespan of a sir2 mutant in the absence of PDE2 in Saccharomyces cerevisiae. J Microbiol. (2017) 55(2):123-129
Kang WK, Kim YH, Kang HA, Kwon K-S, Kim J.-Y. Sir2 phosphorylation through cAMP-PKA and CK2 signaling inhibits the lifespan extension activity of Sir2 in Yeast. eLIFE. (2015) 4:e09709
Moon HY, Cheon SA, Kim H, Agaphonov MO, Kwon O, Oh DB, Kim J-Y*, Kang HA*. (* co-corresponding author) Funtional and transcriptome analyses of Hansenula polymorpha Hac1p, a key UPR transcription factor, reveal a critical function in modulating protein N-glycosylation activity. Appl Environ Micriobiol. (2015) 81(20):6982-6993
Lee HJ, Kim JM, Kang WK, Yang H, Kim J-Y. The NDR kinase Cbk1 downregulates the transcriptional repressor Nrg1 through the mRNA-binding protein Ssd1 in Candida albicans. Euk Cell. (2015) 14(7):671-83.
Bal J, Lee H-J, Cheon SA, Lee KJ, Oh D-B, Kim J-Y. Ylpex5 mutation partially suppresses the defective hyphal growth of a Yarrowia lipolytica ceramide synthase mutant, Yllac1, by recovering lipid raft polarization and vacuole morphogenesis. Fungal Genetics and Biology (2013) 50:1-10
Cheon SA, Bal J, Song Y, Hwang HM, Kim AR, Kang WK, Kang HA, Hannibal-Bach HK, Knudsen J, Ejsing CS, Kim J-Y. Distinct roles of two ceramide synthases, CaLag1p and CaLac1p, in the morphogenesis of Candida albicans. Mol Microbiol. (2012) 83(4):728-745
Kim J-Y, Oh MH, Bernard LP, Macara I, Zhang H. The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. J. Biol. Chem. (2011) In press.
Park J-N, Song Y, Cheon SA, Kwon O, Oh D-B, Jigami Y, Kim J-Y*, Kang HA* (*Co-corresponding) Essential role of YlMPO1, a novel Yarrowia lipolytica homologue of Saccharomyces cerevisiae MNN4, in mannosylphosphorylation of N-and O-linked glycans. Appl. Environ. Microbiol. (2011) 77:1187-1195
Oh MH, Cheon SA, Kang HA, Kim JY. Functional characterization of the unconventional splicing of Yarrowia lipolytica HAC1 mRNA induced by unfolded protein response. Yeast. (2010) 27: 443-452
Eun Young Cho, Seon Ah Cheon, Hyunah Kim, Jinho Choo, Dong-Jik Lee, Ho Myung Ryu, Sang Ki Rhee, Bong-Hyun Chung, Jeong-Yoon Kim, Hyun Ah Kang. Multiple-yapsin-deficient mutant strains for high-level production of intact recombinant proteins in Saccharomyces cerevisiae J Biotechnol (2010) 149: 1-7
Seon Ah Cheon. Jinho Choo, Vera M. Ubiyvovk, Jeong-Nam Park, Moo Woong Kim, Doo-Byoung Oh, Ohsuk Kwon, Andriy A. Sibirny, Jeong-Yoon Kim and Hyun Ah Kang. New selectable host–-marker systems for multiple genetic manipulations based on TRP1, MET2 and ADE2 in the methylotrophic yeast Hansenula polymorpha Yeast (2009) Yeast 26: 507–521.
Yunkyoung Song, Seon Ah Cheon, Kyung Eun Lee, So-Yeon Lee, Byung-Kyu Lee, Doo-Byung Oh, Hyun Ah Kang, and Jeong-Yoon Kim. Role of the RAM Network in Cell Polarity and Hyphal Morphogenesis in Candida albicans. Molecular Biology of the Cell (2008) 19: 5456–5477
Yoon SW, Lee CH, Kim JY, Kim JY, Sung MH, Poo H. Lactobacillus casei secreting alpha-MSH induces the therapeutic effect on DSS-induced acute colitis in Balb/c Mice. J Microbiol Biotechnol. (2008) 18(12):1975-83.
Park SW, Chung MG, Lee HY, Kim JY, Rhee YH. Stable expression and secretion of polyhydroxybutyrate depolymerase of Paucimonas lemoignei in Escherichia coli. J Microbiol. (2008) 46(6):662-9.
Kwon JS, Bal J, Hwang HM, Kim JY. A circularly permuted beta-lactamase as a novel reporter for evaluation of protein cyclization efficiency. J Microbiol. (2008) 46(4):456-61.
Yoon SW, Chun JS, Sung MH, Kim JY, Poo H. alpha-MSH inhibits TNF-alpha-induced matrix metalloproteinase-13 expression by modulating p38 kinase and nuclear factor kappaB signaling in human chondrosarcoma HTB-94 cells. Osteoarthritis Cartilage. (2008) 16(1):115-24.
Song Y, Choi MH, Park J-N, Kim MW, Kim EJ, Kang HA, and Kim J-Y. Engineering of the yeast Yarrowia lipolytica for the production of glycoproteins lacking the outer chain mannose residues of N-glycans. Appl. Environ. Microbiol. (2007) 73(4): 4446-4454
Kang WK, Park E-K, Lee HS, Park B-Y, Chang J-Y, Kim M-Y, Kang HA, and Kim, J-Y. A biologically active angiogenesis inhibitor, human serum albumin-TIMP-2 fusion protein, secreted from Saccharomyces cerevisiae. Prot. Exp. Purif. (2007) 53: 331-338
Hwang JS, Seo DH and Kim J-Y. Soluble forms of YlCrh1p and YlCrh2p, cell wall proteins of Yarrowia lipolytica, have beta-1,3-glycosidase activity. Yeast (2006) 23:803-812.
Song Y and Kim J-Y. Role of CaBud6p in the Polarized Growth of Candida albicans. J. Microbiol. (2006) 44(3):311-319
Kim MW, Kim EJ, Kim J-Y, Park J-S, Oh DB, Shimma Y, Chiba I, Jigami Y, Rhee SK and Kang HA. Functional Characterization of the Hansenular polymorpha HOC1, OCH1, and OCR1 genes as members of the yeast OCH1mannosyltransferase family involved in protein glycosylation. J. Biol. Chem. (2006) 281(10): 6261-6272.
Kang HA, Kang WK, Go, SM, Rezaee A, Krishna SH, Rhee SK, Kim J-Y. Characteristics of Saccharomyces cerevisiae gal1Delta and gal1Deltahxk2Delta mutants expressing recombinant proteins from the GAL promoter. Biotechnol Bioeng. (2005) 89(6):619-629.
Kim MW, Rhee SK, Kim JY, Shimma Y, Chiba Y, Jigami Y, Kang HA. Characterization of N-linked oligosaccharides assembled on secretory recombinant glucose oxidase and cell wall mannoproteins from the methylotrophic yeast Hansenula polymorpha. Glycobiology. (2004) 14(3):243-251.
Heo J-H, Hong WK, Cho EY, Kim MW, Kim J-Y, Kim CH, Rhee S.K, and Kang HA. Properties of the Hansenula polymorpha-derived constitutive GAP promoter, assessed using an HSA reporter gene. FEMS Yeast Research (2003) 4:175-184.
Song Y, Cheon SA, Lee S-Y, Hwang J-S, and Kim J-Y. Isolation and Characterization of Bud6p, an actin interacting protein, form Yarrowia lipolytica. J. Microbiol. (2003) 41(2):121-128
Choi GG, Kim MW, Kim J-Y, and Rhee YH Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with high molar fractions of 3-hydroxyvalerate by a threonine-overproducing mutant of Alcaligenes sp. SH-69. Biotechnol. Lett. (2003) 25:665-670
Ryu HM, Kang WK, Kang HA, and Kim J-Y. Secretion of active urokinase-type plasminogen activator from the yeast Yarrowia lipolytica. Biotechnol. Bioprocess Eng. (2003) 8:162-165
Cheon SA, Han EJ, Kang HA, Ogrydziak DM, and Kim J-Y. Isolation and characterization of the TRP1 gene from the yeast Yarrowia lipolytica and multiple gene disruption using a TRP blaster. Yeast (2003) 20(8): 677-685
Kim J, Cheon SA, Song Y, and Kim J-Y. Cloning and characterization of the multiprotein bridging factor 1 (YlMBF1) gene from the dimorphic yeast Yarrowia lipolytica. J. Microbiol. (2002) 40(2):173-177
Kim MW, Agaphonov MO, Kim J-Y, Rhee SK, and Kang HA. Sequencing and functional analysis of the Hansenula polymorpha genomic fragment containing the YPT1 and PMI40 genes. Yeast (2002) 19:863-871
Kang HA, Kang W, Hong WK, Kim MW, Kim J-Y, Sohn J-H, Choi E-S, Choe K-B, and Rhee SK. Development of expression systems for the production of recombinant human serum albumin using the MOX promoter in Hansenula polymorpha DL-l. Biotechnol. Bioeng. (2001) 76(2):175-185
Kim EA, Lee JG, Whang MK, Park HM, Kim JY, Chae SK, and Maeng PJ. Controlled expression and secretion of Aspergillus oryzae alkaline protease in Aspergillus nidulans. J. Microbiol. (2001) 39(2): 95-101.
Yang J, Kang HA, Ko S-M, Chae S-K, Ryu, DDY, and Kim J-Y. Cloning of the Aspergillus niger pmrA gene, a homologue of yeast PMR1, and characterization of a pmrA null mutant. FEMS Microbiol. Lett. (2001) 199(1):97-102
Lee HH, Chae SK, Kim J-Y, Maeng P.J, and Park HM. Genomic organization of the ancop gene for α-COP homolog from Aspergillus nidulans. Mycobiology. (2000) 28(4):171-176
Kim J, Cheon SA, Park S, Song Y, and Kim J-Y. Serum-induced hypha formation in the dimorphic yeast Yarrowia lipolytica. FEMS Microbiol. Lett. (2000) 190: 9-12
Kim MW, Ko S-M, Kim J-Y, Sohn J-H, Choi E-S, Kang HA, and Rhee S-K. Effect of a PMR1 disruption on the procesing of heterologous glycoproteins secreted in the yeast Saccharomyces cerevisiae. Biotechnol. Bioprocess Eng. (2000) 5(4):234-241
Kim J-W, Park TJ, Ryu DDY, and Kim J-Y. High cell density cultivation of Yarrowia lipolytica using a one-step feeding process. Biotechnol. Prog. (2000) 16:657-660
Kang HA, Choi E-S, Hong W-K, Kim J-Y, Ko S-M, Shon J-H, Rhee S-K. Proteolytic stability of recombinant human serum albumin secreted in the yeast Saccharomyces cerevisiae Appl. Microbiol. Biotechnol (2000) 53(5):575-582
